This cutting-edge psychedelic tech company with its roots in innovative cannabis treatment modalities has developed a patent-pending nasal spray for microdosing psilocybin --and users love it.
By Silo Wellness – December 3, 2019
Silo Wellness, an Oregon company with a team with roots in cannabis delivery modalities, has developed a magic mushroom nasal spray for controlled, metered-dosing consumer microdosing. The company predicts that new users will be more drawn to experimenting with psilocybin’s wellness effects with convenient microdosing before they commit to the full-blow psychedelic “trip” sessions.
“I love our product and can’t wait until it’s legal in the United States, so we can share it with crime victims and first responders,” Silo Wellness founder Mike Arnold said. After formulating the product in Jamaica (where mushrooms are legal) with a team led by Missouri pharmacologist Parag Bhatt and company COO and Marine combat veteran Scott Slay, team members first tested the product on themselves before taking volunteers’ testimonials in private microdosing sessions.
The “Origin Story” of Silo Wellness and their Metered-Dosing Solutions
The visionary inventors of Silo Wellness’s first product to be publicly disclosed under their intellectual property have been working on this project since before the "mush rush" craze reached the media and capital markets.” “National media didn’t care about psychedelics until Denver passed their decriminalization ballot measure,” Arnold stated. “Before that, everyone thought I was crazy when I told them that we were entering the medicinal psychedelics space in advance of Oregon legalizing in 2020.”
The “Shroom Boom” is the “New Cannabis Green Rush” and the Peer-Reviewed Studies Are Even Stronger than Marijuana
With ROI reducing in cannabis startups in Canada and the United States, Arnold watched investors and hopeful entrepreneurs in his home state of Missouri still blindly running full speed to the new Missouri medical marijuana market, as it was gearing up to pass in 2018. “While everyone else saw the excitement for Missouri cannabis as a good sign for an investment, I saw it as the death nail. When everyone is running in one direction, that’s the last place an entrepreneur or investor wants to be. If you were on time for cannabis, you were already too late.”
That’s why Silo Wellness began working with the inventor of the patent-pending Mystabis hemp and marijuana inhalers, Michael Hartman, to begin the brainstorming for their newest product line of metered-dosing solutions.
“I came a little late to the magic mushroom space as a user,” Arnold continued. “I had no information about the medicinal benefits for PTSD and anxiety until I met a doctor while traveling in the spring of 2018 who blew my mind with the research and offered to take me on a guided meditation with mushrooms right there on the spot. I told him I was terrified to use them. ‘How do you know how much you are ingesting? What if I take too much?’ I asked.”
“He replied, ‘Mike, you know me; I’m a doctor.’ Enough said,” Arnold recalls. “I trusted him and it changed my life. Mushrooms have been life-changing and I want to share this healing opportunity with the world with a purpose-driven company mindful of consumer access to these gifts of nature.”
The World’s First Nasal Spray Makes Psilocybin Accessible to the Masses with Predictable Dosing
After that first experience very late in life, then-41-year-old Arnold, couldn’t stop thinking about how to bring this to the masses as quickly and inexpensively as possible.
“In the meantime, I couldn’t help to think how fortunate I was to have an actual physician take me on my first trip rather than ‘some guy’ I know,” Arnold continued. “But I realized that most first-time users don’t have that luxury. Then it hit me. This is a business problem in need of a solution. I reached out to my long-time colleague from the marijuana space, brilliant inventor Michael Hartman, and we agreed that we need to be able to give patients predictable dosing so they can self-titrate into the desired levels of sub-psychedelic or psychedelic treatment.”
“We solved the age-old problem with plant- and fungus-based medicine: How do you know how much is a dose?” Hartman explained. “How do you avoid taking too much, like the cannabis edibles dilemma? We also managed to solve one of the common complaints of some mushroom users: taste and upset stomach.”
Innovated Nasal Spray Solves Several Problems that Keep Many Away from this Medicine
The key to the nasal spray is that it bypasses the gut, going directly to the bloodstream through the nasal mucus membranes and eventually the liver for metabolizing.
“Many psilocybin patients, particularly women, complain of upset stomach or vomiting when taking high-doses of mushrooms,” Board Advisor and Silo Wellness investor Becky Rotterman, a Missouri pharmacist, stated. “We want to bring this wonderful natural medicine first to Oregon and then the flyover states – to those who would be afraid to eat a handful of fungi and who feel more comfortable seeing their medicine in a familiar delivery modality, such as a metered-dose nasal spray.”
User’s Love the Product
Users of the world’s first psilocybin nasal spray have reported satisfactory experiences with this consumer product. One volunteer, Sven (a visual artist and photographer from the Netherlands), was in Jamaica on a photo shoot when he had the opportunity to sample the psilocybin nasal spray. He said that with one microdose spray in each nostril he had a “mellow effect” within 15 minutes with the perceivable effects lasting for approximately 45 minutes. He said he enjoyed the smell and the taste and that it was a “nice sensation” when he initially dosed with the product. He went on to explain that the nasal spray made the mushroom taste “more doable” than eating mushrooms.
The Future of Psychedelic Startups
Regarding the expansion of legalization efforts, Arnold explained that “this is the sort of product that activists can discuss with their legislators to show that safe consumption is possible within a legal framework.”
“With proof of concept in hand, we are taking pre-orders and entertaining licensing proposals for research abroad and manufacturing for the product in advance of jurisdictions coming online legally, similar to Oregon’s proposed medical-marijuana-like psilocybin initiative,” COO Scott Slay, of Eugene, Oregon stated. “The feedback and interest have been tremendous.”
“We are so grateful for the opportunity to have an actual and real first-to-market consumer product in magic mushrooms,” Slay continued. “Most of us were too early to cannabusiness or too late. I found mushrooms after returning from Iraq working in IED demolition and combat. The war changed me and the VA was ill equipped to help me transition and deal with my PTSD. I was heavily medicated. Mushrooms and DMT saved me. My life was renewed. I now have peace and purpose, and I can’t wait to share this opportunity with the world.”
“This isn’t a ‘plan’ to develop a product or a ‘plan’ to open a facility,” Hartman stated. “We have real proof of concept and continued research and development underway—not just an idea. We have developed this and have already received user testimonials. We have been in the space for over a year planning this. The future is now and we are ready.”
The Therapeutic Benefits of Psychedelic Mushrooms
Before the vote in Denver, the Silo Wellness team was already following the Oregon initiative petition process and began working on the concepts that led to their research and development. Microdosing alternatives with faster uptake speed are important to prevent accidental high-dosage experiences. Since psilocybin and other psychoactive compounds are found in nearly 200 known-species of mushrooms, humans have evolved around these beneficial chemical compounds.
Users of psychedelics have known for many years that small “micro doses” of mushrooms can give the user spiritual, medical, and therapeutic benefits without sending the user into a psychedelic “trip” as with high doses of mushroom biomass. Psilocybin is thought to stimulate receptors in the brain and potentially “rewire the brain” by increasing neuro connectivity.
Psilocybin has recently been given its second “Breakthrough Therapy” designation for treatment resistant depression by the FDA.
Silo Wellness, is an Oregon-based psychedelics intellectual property holding company, with operations in Jamaica and beyond. www.SiloWellness.com
SOURCE: Silo Wellness
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